SCIENCE

Led by World Class Science

Co-founded by world-renowned scientist, Prof. Dennis Lo, Insighta stands at the forefront of life sciences innovation. Leveraging Prof. Lo's groundbreaking work in non-invasive testing and backed by a team of world-class researchers, Insighta is set on a path to redefine early cancer detection. The goal – a simple blood draw to detect multiple types of cancers at their early stages, affordable enough for the World. This transformative approach is designed to drastically improve treatment success rates and ultimately save countless lives. Through this commitment to scientific excellence, Insighta aims to make early cancer detection an accessible reality for all, turning a new page in the global fight against cancer.
Co-founded by world-renowned scientist, Prof. Dennis Lo, Insighta stands at the forefront of life sciences innovation. Leveraging Prof. Lo's groundbreaking work in non-invasive testing and backed by a team of world-class researchers, Insighta is set on a path to redefine early cancer detection. The goal – a simple blood draw to detect multiple types of cancers at their early stages, affordable enough for the World. This transformative approach is designed to drastically improve treatment success rates and ultimately save countless lives. Through this commitment to scientific excellence, Insighta aims to make early cancer detection an accessible reality for all, turning a new page in the global fight against cancer.

Quantum Leap FRAGMA
Liquid Biopsy Platform

Proprietary cfDNA Technology

Epigenetics is the modification of DNA that affect it’s behaviour without changing the DNA sequencing. Fragmentation pattern of plasma DNA can be used as an epigenetics-based cancer test.
FRAGMA
Convolutional Neural Network
Somatic
Alterations
Methylation

About FRAGMA Technology

FRAGMA provides an accurate and low cost method for studying the genomewide methylation profile of circulating DNA. As DNA methylation changes are hallmarks for a wide variety of cancers, this can be potentially applied to a multi-cancer early detection test.
Accurate and early detection of liver cancer
Versatile technology can be potentially applied for Multi-Cancer Early Detection
Initial studies has also shown it is applicable for early detection for lung cancer and colorectal cancer
Low cost, enabling accessibility of early cancer detection to a much wider population than current testing methods.
Urine DNA has shown to be valuable for the early detection of urogenital cancers
PUBLICATION
2022.10.26

Epigenetic analysis of cell-free DNA by fragmentomic profiling

Authors
Qing Zhou, Guannan Kang, Peiyong Jiang, Rong Qiao, W. K. Jacky Lam, Stephanie C. Y. Yu, Mary-Jane L. Ma, Lu Ji, Suk Hang Cheng, Wanxia Gai, Wenlei Peng, Huimin Shang, Rebecca W. Y. Chan, Stephen L. Chan, Grace L. H. Wong, Linda T. Hiraki, Stefano Volpi, Vincent W. S. Wong, John Wong, Rossa W. K. Chiu, K. C. Allen Chan, Y. M. Dennis Lo
Go to PNAS Journal
For Humanity. Saving Lives Through Early Cancer Detection.
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